I finally located the marriage record for an ancestor of my wife. It was the first marriage for him and the one from which my wife did not descend. However on a whim, I "googled" the name of the minister. Turns out he was well known in his area, founded what is now nationally known university, and involved in many activties in the mid-nineteenth century.
Also because of googling him, I learned the name of the church and found the email of the church archivist.
I think I'll be googling more minsters. I won't hit paydirt everytime, but one never knows.