If you are stuck on an ancestor, you might consider hiring a professional to solve it for you. Sometimes this is cost prohibitive. Professional genealogists have bills to pay too and need to charge for their research services. However, some will do consulting work--where they read over your organized material and make suggestions. Sometimes that is all you need--suggestions of what to do next.
I did this recently and it was exactly what I needed. Also I really just needed another set of eyes to look over what I had and make certain that I had not overlooked something.
One warning. Organize your information first. Any professional receiving unorganized information will need to organize it. That takes time and increases the number of their billable hours.
A plumber will charge me for his time if he spends fifteen minutes cleaning out the cabinet under the sink before he can actually do any work. It is the same when a professional genealogist has to begin work with your unorganized information. She needs to clean first. That's usually something you can do yourself and save a little money in the process.